First-pass extracted concept

innate immune system

Candidate: concept label1 source documents4 linked claims

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Evidence Snippets

The innate immune system consists of four elements: the epithelial barrier, cells (e.g. macrophages, NK cells), plasma proteins (e.g. complement) and cytokines.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2019Lara D. VeekenDOI PubMed

1 evidence snippet 4 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1disease associationsupports2019Source 1DOI PubMed

The review states that many diseases are linked to innate immune dysregulation, with particular emphasis on autoinflammatory conditions.

Claim 2functional rolesupports2019Source 1DOI PubMed

The review states that innate immunity activates multiple mechanisms to eliminate pathogens and contain infection until adaptive responses are mounted.

Claim 3interplay with adaptive immunitysupports2019Source 1DOI PubMed

The review states that innate immune components act in concert with and help recruit, activate, and differentiate adaptive immune responses.

Claim 4system compositionsupports2019Source 1DOI PubMed

The review describes the innate immune system as comprising epithelial barriers, innate immune cells, plasma proteins such as complement, and cytokines.