First-pass extracted concept

interphase NPC assembly

Candidate: concept label1 source documents3 linked claims

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Aliases

interphase nuclear pore complex assembly

Evidence Snippets

evidence has been accumulating that postmitotic and interphase NPC assembly use fundamentally different mechanisms; the duration, structural intermediates, and regulation by molecular players are different and different types of membrane deformation are involved.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2017FEBS LettersDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1mechanistic distinctionsupports2017Source 1DOI PubMed

Postmitotic and interphase nuclear pore complex assembly use fundamentally different mechanisms.

Claim 2process differencesupports2017Source 1DOI PubMed

Postmitotic and interphase nuclear pore complex assembly differ in duration, structural intermediates, regulation by molecular players, and types of membrane deformation involved.

Claim 3review summarysupports2017Source 1DOI PubMed

In higher eukaryotes with open mitosis, nuclear pore complexes assemble during late mitotic nuclear assembly and during interphase nuclear growth.