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Kif11

Candidate: concept label1 source documents5 linked claims
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Evidence Snippets

Additional inhibitor studies implicated a specific kinesin, Kif11, as participating in HPV pseudogenome delivery to the nucleus.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1localization or proximitysupports2025Source 1DOIPubMed

Kif11, Kif18a, and Kif25 were in proximity to L2 during infection.

Quoted textsource-backed
In addition, Kif11, along with kinesins Kif18a and Kif25, were in proximity to L2 during infection.
Claim 2mechanistic modelsupports2025Source 1DOIPubMed

HPV16 utilizes Kif11 for plus-end movement along mitotic microtubules in the late stage of viral entry.

Quoted textsource-backed
and utilizes Kif11 for plus-end movement in the late stage of viral entry
Claim 3negative interaction resultmixed2025Source 1DOIPubMed

The study was unable to determine a direct interaction between L2 and Kif11.

Quoted textsource-backed
While we were unable to determine a direct interaction between L2 and Kif11
Claim 4perturbation effectsupports2025Source 1DOIPubMed

Relocalization of exogenous Kif11 by an adapted knocksideways approach decreased HPV pseudogenome accumulation to mitotic chromatin.

Quoted textsource-backed
we were able to show via knocksideways approach that relocalization of exogenous Kif11 decreased HPV pseudogenome accumulation to the mitotic chromatin
Claim 5perturbation effectsupports2025Source 1DOIPubMed

Short-term inhibition of Kif11 decreased HPV pseudogenome accumulation at mitotic chromatin.

Quoted textsource-backed
Short-term inhibition of Kif11 decreased HPV pseudogenome accumulation at mitotic chromatin.