Over the past decade, progress has been made toward developing super-resolution techniques that do not require the use of labels.
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label-free super-resolution imaging
Candidate: concept label1 source documents4 linked claims
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A current challenge for label-free super-resolution imaging is reaching resolutions comparable to fluorescence-based methods.
Many label-free super-resolution methods draw inspiration from fluorescence-based STED, PALM, and STORM.
Label-free super-resolution techniques include structured illumination, transient absorption, infrared absorption, and coherent Raman spectroscopies.
Conventional microscopy cannot resolve nanoscale heterogeneities in biological and material samples.