First-pass extracted concept

long-term depression

Candidate: concept label2 source documents2 linked claims

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Aliases

LTD

Evidence Snippets

Results highlight that targeting synaptic plasticity mechanisms, such as long-term potentiation and long-term depression, shows promise.

Evidence 1Source 1DOI PubMedprovenance

we will consider the role of DA as neuromodulator of two forms of synaptic plasticity, known as long-term potentiation (LTP) and long-term depression (LTD)

Evidence 2Source 2DOI PubMedprovenance

Supporting Sources

Source 1primary paper2024Neural Regeneration ResearchDOI PubMed

1 evidence snippet 1 linked claim Claim 1

Source 2review2021CellsDOI PubMed

1 evidence snippet 1 linked claim Claim 1

Linked Claims

Claim 1mechanism targetingsupports2024Source 1DOI PubMed

Targeting synaptic plasticity mechanisms such as long-term potentiation and long-term depression shows promise in these neurodegenerative diseases.

Claim 2plasticity modulation summarysupports2021Source 2DOI PubMed

The review frames dopamine as a neuromodulator of long-term potentiation and long-term depression in several cortical and subcortical areas.