Results highlight that targeting synaptic plasticity mechanisms, such as long-term potentiation and long-term depression, shows promise.
First-pass extracted concept
long-term potentiation
Candidate: concept label3 source documents3 linked claims
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Aliases
LTP
Evidence Snippets
we will consider the role of DA as neuromodulator of two forms of synaptic plasticity, known as long-term potentiation (LTP) and long-term depression (LTD)
The title asks whether plasticity of synapses is the mechanism of long-term memory storage, and the supplied web research summary states that foundational LTP papers establish synaptic plasticity as a memory model discussed by the review.
Supporting Sources
Linked Claims
Targeting synaptic plasticity mechanisms such as long-term potentiation and long-term depression shows promise in these neurodegenerative diseases.
The review frames dopamine as a neuromodulator of long-term potentiation and long-term depression in several cortical and subcortical areas.
Long-term potentiation is treated as a foundational physiological model underlying synaptic plasticity accounts of memory in the review context.