KEGG pathway enrichment highlighted predominant associations with plant-pathogen interaction, plant hormone signal transduction, and the mitogen-activated protein kinase (MAPK) signaling pathway.
First-pass extracted concept
MAPK signaling pathway
Aliases
Mitogen-activated protein kinases, mitogen-activated protein kinase signaling pathway
Evidence Snippets
The present review elucidates the capacity of andrographolide to inhibit signaling pathways, namely... mitogen-activated protein kinase (MAPK) pathways...
These signaling pathways include... mitogen-activated protein kinases (MAPKs)...
Supporting Sources
Linked Claims
Cold-responsive differentially expressed genes in oil palm were enriched for plant-pathogen interaction, plant hormone signal transduction, and MAPK signaling pathways.
KEGG pathway enrichment highlighted predominant associations with plant-pathogen interaction, plant hormone signal transduction, and the mitogen-activated protein kinase (MAPK) signaling pathway.
Cold stress increased superoxide dismutase and peroxidase activities in oil palm seedlings within 4 hours relative to control.
Under cold stress, seedlings displayed a significant increase in superoxide dismutase (SOD, 546.08 U/g min FW) and peroxidase (POD, 153.27 U/g min FW) activities within 4 h compared with the control.
Prolonged cold exposure for 8 hours increased soluble sugar, malondialdehyde, relative electrical conductivity, and carotenoid-to-chlorophyll ratio in oil palm seedlings, consistent with oxidative damage and membrane instability.
Prolonged exposure (8 h) further elevated soluble sugar content (406.27 μg/g FW), malondialdehyde (MDA, 80.22 nmol/g), relative electrical conductivity (109.71%), and the carotenoid-to-chlorophyll ratio, indicating oxidative damage and membrane instability.
Differentially expressed genes in auxin, jasmonic acid, abscisic acid, and brassinosteroid signaling interact with the MAPK cascade to regulate oil palm cold stress adaptation and growth adjustments.
Functional analysis revealed DEGs involved in four major hormone signaling pathways (auxin (AUX/IAA), jasmonic acid (JA), abscisic acid (ABA), and brassinosteroid (BR)), which also interact with the MAPK cascade to collectively regulate oil palm cold stress adaptation and growth adjustments.
The review summarizes that several natural compounds modify multiple inflammation-associated signaling pathways, including NF-κB, AP-1, PTKs, MAPKs, Nrf2, PI3K/AKT, and the ubiquitin-proteasome system.
Through current study, an attempt is made to outline and highlight a wide variety of inflammation-associated signaling pathways that have been modified by several natural compounds. These signaling pathways include nuclear factor-kappa B (NF-κB), activator protein (AP)-1, protein tyrosine kinases (PTKs), mitogen-activated protein kinases (MAPKs), nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factors, tyrosine phosphatidylinositol 3-kinase (PI3K)/AKT, and the ubiquitin-proteasome system.