First-pass extracted concept

MAPK signaling pathway

Candidate: concept label3 source documents5 linked claims
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Aliases

Mitogen-activated protein kinases, mitogen-activated protein kinase signaling pathway

Evidence Snippets

KEGG pathway enrichment highlighted predominant associations with plant-pathogen interaction, plant hormone signal transduction, and the mitogen-activated protein kinase (MAPK) signaling pathway.
Evidence 1Source 1DOIPubMedprovenance
The present review elucidates the capacity of andrographolide to inhibit signaling pathways, namely... mitogen-activated protein kinase (MAPK) pathways...
Evidence 2Source 2DOIPubMedprovenance
These signaling pathways include... mitogen-activated protein kinases (MAPKs)...
Evidence 3Source 3DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1pathway enrichmentsupports2025Source 1DOIPubMed

Cold-responsive differentially expressed genes in oil palm were enriched for plant-pathogen interaction, plant hormone signal transduction, and MAPK signaling pathways.

Quoted textsource-backed
KEGG pathway enrichment highlighted predominant associations with plant-pathogen interaction, plant hormone signal transduction, and the mitogen-activated protein kinase (MAPK) signaling pathway.
Claim 2physiological responsesupports2025Source 1DOIPubMed

Cold stress increased superoxide dismutase and peroxidase activities in oil palm seedlings within 4 hours relative to control.

Quoted textsource-backed
Under cold stress, seedlings displayed a significant increase in superoxide dismutase (SOD, 546.08 U/g min FW) and peroxidase (POD, 153.27 U/g min FW) activities within 4 h compared with the control.
Claim 3physiological responsesupports2025Source 1DOIPubMed

Prolonged cold exposure for 8 hours increased soluble sugar, malondialdehyde, relative electrical conductivity, and carotenoid-to-chlorophyll ratio in oil palm seedlings, consistent with oxidative damage and membrane instability.

Quoted textsource-backed
Prolonged exposure (8 h) further elevated soluble sugar content (406.27 μg/g FW), malondialdehyde (MDA, 80.22 nmol/g), relative electrical conductivity (109.71%), and the carotenoid-to-chlorophyll ratio, indicating oxidative damage and membrane instability.
Claim 4regulatory mechanismsupports2025Source 1DOIPubMed

Differentially expressed genes in auxin, jasmonic acid, abscisic acid, and brassinosteroid signaling interact with the MAPK cascade to regulate oil palm cold stress adaptation and growth adjustments.

Quoted textsource-backed
Functional analysis revealed DEGs involved in four major hormone signaling pathways (auxin (AUX/IAA), jasmonic acid (JA), abscisic acid (ABA), and brassinosteroid (BR)), which also interact with the MAPK cascade to collectively regulate oil palm cold stress adaptation and growth adjustments.
Claim 5review scope summarysupports2023Source 3DOIPubMed

The review summarizes that several natural compounds modify multiple inflammation-associated signaling pathways, including NF-κB, AP-1, PTKs, MAPKs, Nrf2, PI3K/AKT, and the ubiquitin-proteasome system.

Quoted textsource-backed
Through current study, an attempt is made to outline and highlight a wide variety of inflammation-associated signaling pathways that have been modified by several natural compounds. These signaling pathways include nuclear factor-kappa B (NF-κB), activator protein (AP)-1, protein tyrosine kinases (PTKs), mitogen-activated protein kinases (MAPKs), nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factors, tyrosine phosphatidylinositol 3-kinase (PI3K)/AKT, and the ubiquitin-proteasome system.