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medicinal cannabis drug interactions

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Evidence Snippets

However, pharmacokinetics and pharmacodynamics interactions could be perceived in drug combinations, so in this short review we tried to shed light on the potential drug interactions of medicinal cannabis.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2018MedicinesDOI PubMed

1 evidence snippet 4 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1clinical recommendationsupports2018Source 1DOI PubMed

Responses of cannabis users taking certain drugs should be closely monitored to guard safety, especially in elderly people and those with chronic disease or kidney and liver conditions.

Claim 2evidence gapsupports2018Source 1DOI PubMed

Few data have been provided to healthcare practitioners about drug-drug interactions of cannabinoids with prescription medications.

Claim 3mechanism summarysupports2018Source 1DOI PubMed

Bidirectional effects may be expected when cannabinoids are coadministered with other agents through affected membrane transporters and metabolizing enzymes.

Claim 4review scope statementsupports2018Source 1DOI PubMed

This review addresses potential pharmacokinetic and pharmacodynamic drug interactions of medicinal cannabis.