For targeted manipulation of lipids, we describe pharmacological agents and controllable enzymes, termed membrane editors, that harness optogenetics and chemogenetics.
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membrane editors
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controllable enzymes
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These emerging strategies are revealing new insights into the regulation, dynamics, and functions of lipids in cell biology.
Quoted textsource-backed
Collectively, these strategies are revealing new insights into the regulation, dynamics, and functions of lipids in cell biology.
The paper reviews emerging chemistry-biology tools for studying lipid biology, spanning detection, targeted manipulation, and lipid-protein interaction mapping.
Quoted textsource-backed
In recent years, a plethora of tools bridging the chemistry-biology interface has emerged for studying different aspects of lipid biology. Here, we provide an overview of these approaches.
Membrane editors are controllable enzymes used for targeted manipulation of lipids and are described as harnessing optogenetics and chemogenetics.
Quoted textsource-backed
For targeted manipulation of lipids, we describe pharmacological agents and controllable enzymes, termed membrane editors, that harness optogenetics and chemogenetics.