This research introduces membrane potential as a key component of the complex feedforward mechanism that links the adaptive and excitable networks necessary to guide immune cells in challenging tissue environments.
First-pass extracted concept
membrane potential
Candidate: concept label1 source documents4 linked claims
Live refresh every 5sNext refresh in 5s
Evidence Snippets
Supporting Sources
Linked Claims
Focal depolarization via optogenetics biased pseudopod selection and triggered new protrusions, and this effect depended on Gα signaling.
Quoted textsource-backed
Focal depolarization via optogenetics biased pseudopod selection and triggered new protrusions, which depended on Gα signaling.
Global hyperpolarization caused neutrophils to stall migration.
Quoted textsource-backed
Global hyperpolarization caused neutrophils to stall migration.
Inwardly rectifying potassium channels, particularly Kir7.1 (Kcnj13), maintain resting membrane potential and are crucial for directional sensing during neutrophil chemotaxis.
Quoted textsource-backed
Here, we demonstrate that inwardly rectifying potassium channels, particularly Kir7.1 (Kcnj13), maintain the resting membrane potential and are crucial for directional sensing during neutrophil chemotaxis.
Membrane potential is a key component of a feedforward mechanism linking adaptive and excitable networks to guide immune cells in challenging tissue environments.
Quoted textsource-backed
This research introduces membrane potential as a key component of the complex feedforward mechanism that links the adaptive and excitable networks necessary to guide immune cells in challenging tissue environments.