The abstract includes metabolic engineering among the technologies reshaping pest management.
First-pass extracted concept
metabolic engineering
Extracted Explainers
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Evidence Snippets
Metabolic engineering of Corynebacterium glutamicum for high-yield de novo biosynthesis of 5-aminovaleramide, a promising bio-based monomer.
The review further discusses insect counterstrategies and explores cutting-edge technologies-CRISPR/Cas9, RNA interference, and metabolic engineering that are reshaping pest management.
Growth-coupled bioproduction (GCBP) is a metabolic engineering approach...
Supporting Sources
Linked Claims
The paper reports metabolic engineering of Corynebacterium glutamicum for de novo biosynthesis of 5-aminovaleramide.
In growth-coupled bioproduction, product yield is primarily limited by pathway constraints and these constraints can be overcome by further metabolic engineering.
Integrating growth-coupled bioproduction with metabolic engineering and improved computational design has the potential to reshape industrial biotechnology toward robust and efficient bioproduction.
Challenges for growth-coupled bioproduction include lack of metabolic engineering tools for nonmodel organisms, limited in silico design capabilities, and uncharacterized metabolism.
The source states that major challenges for engineered anti-herbivore traits include limited field validation, ecological trade-offs, and regulatory hurdles.
The source states that CRISPR/Cas9, RNA interference, and metabolic engineering are cutting-edge technologies reshaping pest management.