First-pass extracted concept

metabolic reprogramming in colorectal cancer

Candidate: concept label1 source documents3 linked claims

Jump to evidence Jump to sources Jump to claims

Live refresh every 5sNext refresh in 5s

Aliases

metabolic reprogramming

Evidence Snippets

In recent years, metabolic reprogramming and immunosenescence have received extensive attention as key mechanisms for tumorigenesis, development and treatment resistance.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2025MEDDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1disease mechanismsupports2025Source 1DOI PubMed

Metabolic reprogramming and immunosenescence jointly promote immune escape and therapeutic resistance in colorectal cancer.

Claim 2mechanistic rolesupports2025Source 1DOI PubMed

In colorectal cancer, metabolic reprogramming and immunosenescence are described as key mechanisms in tumorigenesis, development, and treatment resistance.

Claim 3mechanistic rolesupports2025Source 1DOI PubMed

Metabolic reprogramming in colorectal cancer provides energy and biosynthetic precursors for tumor cells and regulates immune responses by reconstructing the tumor microenvironment.