First-pass extracted concept

Methoprene-tolerant

Candidate: concept label1 source documents4 linked claims

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Aliases

Met

Evidence Snippets

MF action is mediated by a transcriptional signaling cascade consisting of Methoprene-tolerant (Met)... Met and Src were characterized as basic helix-loop-helix, Period-Aryl Hydrocarbon Nuclear Translocator-Single-minded protein (bHLH-PAS) TFs.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2026MEDDOI PubMed

1 evidence snippet 4 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1bioinformatic identificationsupports2026Source 1DOI PubMed

Across pancrustacean taxa, 81 Met contigs, 45 Src contigs, 136 Kr-h1 contigs, 66 E93 contigs, 60 CBP contigs, and 172 CtBP contigs were identified.

Claim 2conservationsupports2026Source 1DOI PubMed

Met, Src, Kr-h1, E93, CBP, and CtBP genes are highly conserved across pancrustacean species.

Claim 3pathway compositionsupports2026Source 1DOI PubMed

Methyl farnesoate action is mediated by a transcriptional signaling cascade comprising Met, Src, Kr-h1, E93, CBP, and CtBP.

Claim 4protein domain characterizationsupports2026Source 1DOI PubMed

Met and Src were characterized as bHLH-PAS transcription factors.