This is a translational concept covering interventions that aim to modify microbiome-immune interactions. The abstract presents it as a future application area rather than a defined tool.
First-pass extracted concept
microbiome-targeted therapeutic interventions
Candidate: concept label1 source documents5 linked claims
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Extracted Explainers
What the tool is doing
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Evidence Snippets
Supporting Sources
Linked Claims
Current knowledge has challenges and limitations in achieving causal understanding of host immune-microbiome interactions.
In genetically susceptible hosts and defined environmental contexts, imbalances in microbiota-immunity interactions are believed to contribute to immune-mediated disorders.
The commensal microbiota plays critical roles in training and development of major components of the host innate and adaptive immune system.
The immune system helps maintain key features of host-microbe symbiosis.
Insights into microbiome-immunity interactions may support future development of microbiome-targeted therapeutic interventions.