In addition, miRs have been found in body fluids of patients with different types of diseases, including cancer. Therefore, investigation of miRs can shed light on the process of pathogenesis, and may provide biomarkers for diagnosis and prognosis.
First-pass extracted concept
microRNAs as body-fluid biomarkers
Candidate: concept label1 source documents5 linked claims
Live refresh every 5sNext refresh in 5s
Evidence Snippets
Supporting Sources
Linked Claims
MicroRNAs found in body fluids may provide biomarkers for diagnosis and prognosis.
Quoted textsource-backed
In addition, miRs have been found in body fluids of patients with different types of diseases, including cancer. Therefore, investigation of miRs can shed light on the process of pathogenesis, and may provide biomarkers for diagnosis and prognosis.
A subset of microRNAs is specifically expressed in embryonic stem cells and germ cell cancers, suggesting a role in early embryogenesis and development.
Quoted textsource-backed
A subset of miRs is specifically expressed in ES cells and GCC, suggesting their critical role in early embryogenesis and development.
Specific proteins and microRNAs are reported to control pluripotency and early development.
Quoted textsource-backed
Several reports have demonstrated the role of specific proteins and microRNAs (miRs) in the control of pluripotency and thus early development.
MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression by base-pairing to protein-encoding mRNAs.
Quoted textsource-backed
miRs are small non-coding RNA molecules that post-transcriptionally regulate gene expression by base-paring to protein encoding mRNAs.
MicroRNAs are predicted to regulate up to 30% of human protein-encoding genes.
Quoted textsource-backed
miRs are predicted to regulate up to 30% of the protein-encoding genes within the human genome.