The abstract describes the mTOR pathway as a central regulator that integrates nutrient availability, growth factors, and cellular stress to coordinate anabolic and catabolic processes.
First-pass extracted concept
mTOR pathway
Candidate: concept label1 source documents4 linked claims
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Aliases
mammalian target of rapamycin pathway, mTOR signaling
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Evidence Snippets
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Linked Claims
Dysregulation of the mTOR signaling hub has broad implications for health and disease.
Quoted textsource-backed
The dysregulation of this signaling hub has broad implications for health and disease.
The mTOR pathway integrates intracellular and extracellular cues including nutrient availability, growth factors, and cellular stress.
Quoted textsource-backed
integrating a wide array of intracellular and extracellular cues, including nutrient availability, growth factors, and cellular stress
The mTOR pathway is a central regulator of cellular growth, metabolism, and homeostasis.
Quoted textsource-backed
The mammalian target of rapamycin (mTOR) pathway is a central regulator of cellular growth, metabolism, and homeostasis
The mTOR pathway coordinates anabolic and catabolic processes including protein, lipid, and nucleotide synthesis, autophagy, and proteasomal degradation.
Quoted textsource-backed
to coordinate anabolic and catabolic processes such as protein, lipid, and nucleotide synthesis; autophagy; and proteasomal degradation