We analyzed nanoparticle regulation research to examine the evolution of regulatory frameworks, identify major thematic structures, and evaluate current challenges in the governance of rapidly advancing nanotechnologies.
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nanoparticle regulation
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Six major research topics were identified, including energy and sensor applications, metal oxide toxicity, antibacterial silver nanoparticles, cancer nano-therapy, and nanoparticle-enabled drug and mRNA delivery.
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Six major research topics were identified, spanning energy and sensor applications, metal oxide toxicity, antibacterial silver nanoparticles, cancer nano-therapy, and nanoparticle-enabled drug and mRNA delivery.
The study analyzed 9095 PubMed-indexed articles from January 2015 to October 2025 using text mining, keyword frequency analysis, and topic modeling.
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A total of 9095 PubMed-indexed articles published between January 2015 and October 2025 were analyzed using text mining, keyword frequency analysis, and topic modeling.
Publication output in nanoparticle regulation research increased markedly after 2019.
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Publication output increased markedly after 2019 with interdisciplinary journals driving much of the growth.
Regulatory considerations became increasingly embedded within experimental and biomedical nanoparticle research, especially in safety assessment and environmental impact analyses.
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Regulatory considerations were increasingly embedded within experimental and biomedical research, particularly in safety assessment and environmental impact analyses.