This label captures the tumor cell states that correspond to the invasive, neuronally connected subpopulation described in the abstract.
First-pass extracted concept
neuronal and neural-progenitor-like glioblastoma cell states
Candidate: concept label1 source documents4 linked claims
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Superimposed molecular and functional single-cell data reveal that neuronal mechanisms govern glioblastoma cell invasion on multiple levels.
Quoted textsource-backed
Collectively, superimposing molecular and functional single-cell data revealed that neuronal mechanisms govern glioblastoma cell invasion on multiple levels.
Whole-brain colonization in glioblastoma is fueled by a subpopulation of tumor cells that lack connections with other tumor cells and astrocytes yet receive synaptic input from neurons.
Quoted textsource-backed
Here, we demonstrate that whole-brain colonization is fueled by glioblastoma cells that lack connections with other tumor cells and astrocytes yet receive synaptic input from neurons.
Glioblastoma tumor cell invasion resembles neuronal migration mechanisms and adopts a Lévy-like movement pattern of probing the environment.
Quoted textsource-backed
Tumor cell invasion resembled neuronal migration mechanisms and adopted a Lévy-like movement pattern of probing the environment.
The invasive synaptically connected glioblastoma subpopulation corresponds to neuronal and neural-progenitor-like tumor cell states defined by single-cell transcriptomics.
Quoted textsource-backed
This subpopulation corresponds to neuronal and neural-progenitor-like tumor cell states, as defined by single-cell transcriptomics, both in mouse models and in the human disease.