First-pass extracted concept

nicotinic acetylcholine receptors

Candidate: concept label1 source documents5 linked claims

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Aliases

nicotinic receptors

Evidence Snippets

This review will focus mainly on the fast ionotropic nicotinic receptors and less on the metabotropic muscarinic receptors.

Evidence 1Source 1DOIprovenance

Supporting Sources

Source 1review2014SHILAP Revista de lepidopterologíaDOI

1 evidence snippet 5 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1behavior mechanismsupports2014Source 1DOI

Cholinergic modulation of the medial prefrontal cortex plays a role in attention.

Quoted textsource-backed

Here we will review the evidence that cholinergic modulation of the mPFC plays a role in attention

Claim 2behavior mechanismsupports2014Source 1DOI

Recent evidence implicates fast phasic release of acetylcholine in cue detection and attention.

Quoted textsource-backed

Recent evidence implicates fast phasic release of acetylcholine in cue detection and attention.

Claim 3evidence gapsupports2014Source 1DOI

Important aspects of how acetylcholine affects neuronal processing in medial prefrontal cortex and influences attention remain unknown.

Quoted textsource-backed

there is still a lot unknown about how this occurs

Claim 4functional rolesupports2014Source 1DOI

Acetylcholine release in the medial prefrontal cortex is crucial for normal cognitive performance.

Quoted textsource-backed

Acetylcholine release in the medial prefrontal cortex is (mPFC) crucial for normal cognitive performance.

Claim 5mechanistic scopesupports2014Source 1DOI

Activation of acetylcholine receptors changes processing in cortical microcircuitry.

Quoted textsource-backed

we will summarize the current knowledge about the role between acetylcholine receptors and behavior and how acetylcholine receptor activation changes processing in the cortical microcircuitry