This meta-analysis aims to systematically compare the type and frequency of adverse effects, tolerability, and acceptability across different brain stimulation techniques and mental disorders.
First-pass extracted concept
non-invasive brain stimulation
Aliases
NIBS
Evidence Snippets
Non-invasive brain stimulations (NIBS), such as transcranial magnetic stimulation, transcranial direct current stimulation, transcranial alternating current stimulation, transcranial focused ultrasound, and transcranial pulse stimulation (TPS), employ electric currents or acoustic waves to induce and modulate neuroplasticity in humans.
Non-invasive brain stimulation (NIBS) has been an increasingly used therapeutic modality for neuropsychiatric disorders in recent decades.
Non-invasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and transcranial ultrasound stimulation (TUS), have emerged as promising alternatives.
Supporting Sources
Linked Claims
The planned review will include randomized controlled trials and prospective non-randomized studies of adverse effects of non-invasive brain stimulation in psychiatric populations, provided adverse-effect frequency is reported in a standardized manner.
Eligible studies include randomised controlled trials (RCTs) that compare active treatments or an active treatment with sham control, including both parallel group and cross-over studies, as well as prospective non-randomised studies such as case-control studies and pre-post studies investigating adverse effects of non-invasive brain stimulation in psychiatric populations. Included studies report on the frequency of adverse effects in a standardised manner.
Adverse-effect data for non-invasive brain stimulation methods in psychiatric use are fragmented and inconsistently reported.
Although these methods show promising efficacy, data on their adverse effects remain fragmented and inconsistently reported.
A network meta-analysis is planned if sufficient data are available and the comparison network is adequately connected.
Provided that sufficient data are available and the network of comparisons is adequately connected, a network meta-analysis will be conducted to compare adverse effects and tolerability across interventions.
The protocol aims to systematically compare adverse-effect type and frequency, tolerability, and acceptability across non-invasive brain stimulation techniques and mental disorders.
This meta-analysis aims to systematically compare the type and frequency of adverse effects, tolerability, and acceptability across different brain stimulation techniques and mental disorders.
Non-invasive brain stimulation shows potential for treating drug-resistant epilepsy.
Epilepsy affects more than 50 million individuals worldwide.
About one-third of epilepsy patients develop drug resistance.
The growing evidence base suggests that newer non-invasive brain stimulation techniques could transform treatment of psychiatric conditions and support integration into clinical practice.
The review suggests that non-invasive brain stimulation alone or in combination with pharmacological therapy is a promising method for patients with epilepsy.
Non-invasive brain stimulation techniques including TMS, tDCS, and TUS have emerged as promising alternatives for epilepsy management.
Clinical application of non-invasive brain stimulation in epilepsy is limited by variability in stimulation protocols and patient responsiveness.
Non-invasive brain stimulation modalities including TPS use electric currents or acoustic waves to induce and modulate neuroplasticity in humans.
Non-invasive brain stimulations (NIBS), such as transcranial magnetic stimulation, transcranial direct current stimulation, transcranial alternating current stimulation, transcranial focused ultrasound, and transcranial pulse stimulation (TPS), employ electric currents or acoustic waves to induce and modulate neuroplasticity in humans.
Non-invasive brain stimulation methods modulate brain activity and have fewer side effects than drug therapy.
In South Asia, particularly in India, use of non-invasive brain stimulation treatment methods has notably increased.
Research into non-invasive neuromodulation in South Asia has expanded significantly but remains predominantly centered in India.
Non-invasive brain stimulation has been increasingly used as a therapeutic modality for neuropsychiatric disorders in recent decades.