In this review, we focus on progress towards engineering of non-opsin-based photosensory domains, and their representative applications in cell biology and physiology.
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non-opsin-based photosensory domains
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Linked Claims
Optogenetic actuators engineered from photoreceptors are widely used to study cell biology and tissue physiology.
Genetically encodable light-sensitive proteins are key building blocks of optogenetic actuators.
There is growing demand for novel photosensory domains with improved optical properties and light-induced responses for broader biological studies.
Most optogenetic photosensory modules are engineered from naturally occurring photoreceptor proteins from bacteria, fungi, and plants.
The source reviews engineering of non-opsin-based photosensory domains and representative applications in cell biology and physiology.