Cone beam computed tomography (CBCT)-based approaches for online adaptive radiation therapy (oART) have recently become clinically available for ultra-hypofractionated prostate stereotactic body radiation therapy (SBRT).
First-pass extracted concept
online adaptive radiation therapy
Candidate: concept label1 source documents4 linked claims
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Aliases
oART
Evidence Snippets
Supporting Sources
Linked Claims
Inter-fractional prostate swelling was responsible for clinical target volume deviations during the adaptive workflow.
Quoted textsource-backed
Inter-fractional prostate swelling ( rTx,Vol(prostate)=0.98,p=0.005) was responsible for CTV deviations.
Compared with IGRT, daily online adaptive radiotherapy improved clinical target volume coverage in ultra-hypofractionated prostate SBRT.
Quoted textsource-backed
oART improved median V40Gy(CTV) from 86% in IGRTCBCT1 to 94% in ARTCBCT2.
Treatment adaptation times should be minimized to reduce morphology-driven constraint violations during CBCT-based online adaptive prostate radiotherapy.
Quoted textsource-backed
Treatment adaptation times should therefore be minimized whenever possible.
Bladder filling and rectal gas migration during adaptation degraded organ-at-risk dosimetry and caused constraint violations.
Quoted textsource-backed
Bladder filling ( rΔT,Vol(bladder)=0.34,p=0.002 ) and rectal gas migration during the median adaptation time ΔT=24.0min increased V37Gy(bladder) from 4.9 cm3 in ARTCBCT1 to 6.5 cm3 in ARTCBCT2 and V36Gy(rectum) from 0.5 cm3 to 0.6 cm3 and led to 10 constraint violations, each.