First-pass extracted concept

opioids

Candidate: concept label1 source documents5 linked claims

Jump to evidence Jump to sources Jump to claims

Live refresh every 5sNext refresh in 5s

Evidence Snippets

Opioids are the most commonly used and effective analgesic treatments for severe pain, but they have recently come under scrutiny owing to epidemic levels of abuse and overdose.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2018Annual Review of NeuroscienceDOI PubMed

1 evidence snippet 5 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1functional effect summarysupports2018Source 1DOI PubMed

The review emphasizes pain-relieving properties of opioids against the affective dimension of the pain experience.

Claim 2mechanism scopesupports2018Source 1DOI PubMed

The review summarizes signaling mechanisms by which opioids regulate neuronal function and neurotransmission.

Claim 3review summarysupports2018Source 1DOI PubMed

Opioids are commonly used and effective analgesic treatments for severe pain.

Claim 4risk summarysupports2018Source 1DOI PubMed

Opioids have come under scrutiny because of epidemic levels of abuse and overdose.

Claim 5site of action scopesupports2018Source 1DOI PubMed

The review discusses loci of opioid analgesic action along peripheral and central pain pathways.