The Opsin 5 (Opn5) group within the animal opsin family comprises a diverse array of related proteins, such as Opn5m... Opn5L1 and Opn5L2... and Opn6...
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Opn5 group
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The Opn5 group comprises multiple related proteins including Opn5m, Opn5L1, Opn5L2, Opn6, and invertebrate Opn5 homologs.
The precise physiological functions and molecular characteristics of Opn5-related proteins remain only partially understood.
Opn5-family proteins form a single clade within animal opsins but differ markedly in retinal binding properties, photoreaction, and G-protein coupling specificity.
Unique molecular characteristics of Opn5-related proteins suggest high potential for use as optogenetic tools through specialized manipulations.