First-pass extracted concept

opto-electronic feedback loop-based system

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Evidence Snippets

we developed an opto-electronic feedback loop-based system integrating cellular electrophysiology, real-time computing, and optogenetic approaches

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1primary paper2023MEDDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1performance under perturbationsupports2023Source 1DOI PubMed

The system accurately restored and preserved cardiac action-potential morphologies in the presence of electrical perturbations of different origin without prior knowledge of the disturbance.

Quoted textsource-backed

This allowed accurate restoration and preservation of cardiac AP morphologies in the presence of electrical perturbations of different origin in an unsupervised, self-regulatory manner, without any prior knowledge of the disturbance.

Claim 2tool capabilitysupports2023Source 1DOI PubMed

The reported opto-electronic feedback loop system enables real-time control of action-potential morphology in excitable cells.

Quoted textsource-backed

we developed an opto-electronic feedback loop-based system integrating cellular electrophysiology, real-time computing, and optogenetic approaches and applied it to monolayers of heart muscle cells

Claim 3waveform enforcementsupports2023Source 1DOI PubMed

The system could enforce arbitrary action-potential waveforms onto heart muscle cell monolayers.

Quoted textsource-backed

Moreover, arbitrary AP waveforms could be enforced onto these cells.