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optogenetic negative-feedback gene circuits

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Here, we engineer optogenetic negative-feedback gene circuits in mammalian cells to achieve noise-reduction for precise gene expression control.

Evidence 1Source 1DOIprovenance

Here, we engineer optogenetic gene circuits into mammalian cells to achieve noise-reduction for precise gene expression control by genetic, in vitro negative feedback.

Evidence 2Source 2DOI PubMedprovenance

Supporting Sources

Source 1primary paper2019DOI

1 evidence snippet 1 linked claim Claim 1

Source 2primary paper2019Nucleic Acids ResearchDOI PubMed

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Linked Claims

Claim 1engineering outcomesupports2019Source 1DOI

The authors engineered optogenetic negative-feedback gene circuits in mammalian cells for noise-reduced precise gene expression control.

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Here, we engineer optogenetic negative-feedback gene circuits in mammalian cells to achieve noise-reduction for precise gene expression control.