First-pass extracted concept

optogenetic stimulation of the auditory pathway

Candidate: concept label1 source documents4 linked claims
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Aliases

cochlear optogenetics

Evidence Snippets

Our study demonstrates a strategy for optogenetic stimulation of the auditory pathway in rodents and lays the groundwork for future applications of cochlear optogenetics in auditory research and prosthetics.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1application effectsupports2014Source 1DOIPubMed

Optogenetic stimulation of spiral ganglion neurons restored auditory activity in deaf mice.

Quoted textsource-backed
Furthermore, optogenetic stimulation of SGNs restored auditory activity in deaf mice.
Claim 2comparative performancesupports2014Source 1DOIPubMed

Optogenetic stimulation achieved better frequency resolution than monopolar electrical stimulation in the cochlea.

Quoted textsource-backed
Approximation of the spatial spread of cochlear excitation by recording local field potentials (LFPs) in the inferior colliculus in response to suprathreshold optical, acoustic, and electrical stimuli indicated that optogenetic stimulation achieves better frequency resolution than monopolar electrical stimulation.
Claim 3mechanistic effectsupports2014Source 1DOIPubMed

Optogenetic stimulation of spiral ganglion neurons activated the auditory pathway.

Quoted textsource-backed
Optogenetic stimulation of spiral ganglion neurons (SGNs) activated the auditory pathway, as demonstrated by recordings of single neuron and neuronal population responses.
Claim 4strategy statementsupports2014Source 1DOIPubMed

The study demonstrates a strategy for optogenetic stimulation of the auditory pathway in rodents and motivates future auditory research and prosthetic applications.

Quoted textsource-backed
Our study demonstrates a strategy for optogenetic stimulation of the auditory pathway in rodents and lays the groundwork for future applications of cochlear optogenetics in auditory research and prosthetics.