Phosphoinositides are signalling lipids derived from phosphatidylinositol... now widely recognized as key integrators of membrane dynamics that broadly impact on all aspects of cell physiology and on disease.
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phosphoinositides
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In endocytic and exocytic pathways, phosphoinositides direct membrane flow and vesicular traffic is coupled to phosphoinositide conversion.
Non-vesicular exchange of lipids, ions, and metabolites at membrane contact sites depends on phosphoinositides.
Phosphoinositides have important roles in autophagy and the endolysosomal system that reshape understanding of lysosome biology.
Phosphoinositides are broadly recognized as key integrators of membrane dynamics that affect cell physiology and disease.