Light-based therapeutic and imaging modalities, which emerge in clinical applications, rely on molecular tools, such as photocleavable protecting groups and photoswitches that respond to photonic stimulus and translate it into a biological effect.
First-pass extracted concept
photoresponsive molecular tools
Candidate: concept label1 source documents4 linked claims
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The review uses medical imaging, drug delivery, and photopharmacology as application scenarios to define desired properties of photoresponsive tools for controlling biological function.
Quoted textsource-backed
we use those scenarios to explain the necessary properties that the photoresponsive tools used to control biological function should possess, highlighted by examples from medical imaging, drug delivery and photopharmacology.
For medical application, key photoresponsive-tool parameters requiring optimization include activation wavelength, band separation, fatigue resistance, and half-life.
Quoted textsource-backed
However, optimisation of their key parameters (activation wavelength, band separation, fatigue resistance and half-life) is necessary to enable application in the medical field.
Emerging clinical light-based therapeutic and imaging modalities rely on photoresponsive molecular tools including photocleavable protecting groups and photoswitches.
Quoted textsource-backed
Light-based therapeutic and imaging modalities, which emerge in clinical applications, rely on molecular tools, such as photocleavable protecting groups and photoswitches that respond to photonic stimulus and translate it into a biological effect.
Pharmacological aspects including toxicity, solubility, and stability are important considerations for light-responsive molecules intended for medical use.
Quoted textsource-backed
an outlook is given on pharmacological aspects (toxicity, solubility, and stability) of light-responsive molecules.