First-pass extracted concept

PI3K/AKT/mTOR signaling pathway

Candidate: concept label2 source documents1 linked claims

Jump to evidence Jump to sources Jump to claims

Live refresh every 5sNext refresh in 5s

Evidence Snippets

This article summarizes available information on the effects of pentacyclic triterpenoids on the PI3K/AKT/mTOR ... signaling pathways in ovarian cancer cells.

Evidence 1Source 1DOI PubMedprovenance

The present review elucidates the capacity of andrographolide to inhibit signaling pathways, namely... phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)...

Evidence 2Source 2DOI PubMedprovenance

Supporting Sources

Source 1primary paper2025MEDDOI PubMed

1 evidence snippet 1 linked claim Claim 1

Source 2review2024MEDDOI PubMed

1 evidence snippet 0 linked claims

Linked Claims

Claim 1review scopesupports2025Source 1DOI PubMed

The article summarizes available information on the effects of pentacyclic triterpenoids on PI3K/AKT/mTOR, MAPK/ERK, NF-κB, JAK/STAT, Notch, HIF-1α, TGF-β, Wnt/β-catenin, Hippo, and Hedgehog signaling pathways in ovarian cancer cells.

Quoted textsource-backed

This article summarizes available information on the effects of pentacyclic triterpenoids on the PI3K/AKT/mTOR, MAPK/ERK, NF-κB, JAK/STAT, Notch, HIF-1α, TGF-β, Wnt/β-catenin, Hippo, and Hedgehog signaling pathways in ovarian cancer cells.