First-pass extracted concept

primary mesenchyme cells

Candidate: concept label1 source documents4 linked claims
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Aliases

PMC, PMCs

Evidence Snippets

the biomineralization process can be investigated in a well-defined, single cell type (the primary mesenchyme cell)
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1cellular mechanism summarysupports1988Source 1DOIPubMed

Primary mesenchyme cells are responsible for assembly of the sea urchin embryonic skeleton and originate from a subset of micromeres formed in the 16-cell embryo.

Quoted textsource-backed
the cells responsible for assembly of the skeleton are primary mesenchyme cells and that they originate from a subset of the micromeres formed in the 16-cell embryo
Claim 2in vitro differentiation summarysupports1988Source 1DOIPubMed

Isolated micromeres, but not meso- or macromeres, can differentiate in vitro into spicule-forming primary mesenchyme cells in sea water containing serum, suggesting intrinsic programming for this differentiation process.

Quoted textsource-backed
isolated micromeres (but not meso- or macromeres) cultivated in sea water containing serum could differentiate in vitro into spicule-forming primary mesenchyme cells
Claim 3morphogenesis summarysupports1988Source 1DOIPubMed

The morphology of the spicule is dictated by the syncytial structure produced by primary mesenchyme cells rather than by the arrangement of microcrystals alone.

Quoted textsource-backed
such microcrystals do not define the overall shape of the spicule. Rather, the morphology of the spicule is dictated by the syncytial structure produced by the primary mesenchyme cells
Claim 4review scope summarysupports1988Source 1DOIPubMed

The sea urchin embryo provides a system in which biomineralization can be investigated in a well-defined single cell type, the primary mesenchyme cell.

Quoted textsource-backed
this biological system, in which the biomineralization process can be investigated in a well-defined, single cell type (the primary mesenchyme cell)