The review names proximity labeling as a molecular tool class relevant to decoding cell-cell communication. It is framed as providing molecular-level information about multicellular interactions.
First-pass extracted concept
proximity labeling
Candidate: concept label3 source documents8 linked claims
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Aliases
PL
Extracted Explainers
Evidence Snippets
To conclude, we survey techniques for elucidating lipid-protein interactions, including photoaffinity labeling and proximity labeling.
This review, emerging from forum discussions, highlights the latest advancements in molecular tools-such as ... proximity labeling...
Research in this area has been greatly accelerated by the invention of proximity labeling (PL) techniques. By employing engineered enzymes capable of tagging proteins and other molecules in vivo, PL allows real-time mapping of biomolecular interactions within native environments.
Supporting Sources
Linked Claims
In plants, proximity labeling has emerged as a powerful tool despite unique implementation challenges.
Quoted textsource-backed
In plants, the implementation of PL presents unique challenges but has nonetheless emerged as a powerful tool.
Proximity labeling techniques have accelerated research on capturing protein-protein interactions in living organisms.
Quoted textsource-backed
Research in this area has been greatly accelerated by the invention of proximity labeling (PL) techniques.
These emerging strategies are revealing new insights into the regulation, dynamics, and functions of lipids in cell biology.
Quoted textsource-backed
Collectively, these strategies are revealing new insights into the regulation, dynamics, and functions of lipids in cell biology.
Proximity labeling uses engineered enzymes to tag proteins and other molecules in vivo, enabling real-time mapping of biomolecular interactions in native environments.
Quoted textsource-backed
By employing engineered enzymes capable of tagging proteins and other molecules in vivo, PL allows real-time mapping of biomolecular interactions within native environments.
The paper reviews emerging chemistry-biology tools for studying lipid biology, spanning detection, targeted manipulation, and lipid-protein interaction mapping.
Quoted textsource-backed
In recent years, a plethora of tools bridging the chemistry-biology interface has emerged for studying different aspects of lipid biology. Here, we provide an overview of these approaches.
Super-resolution imaging, proximity labeling, bioorthogonal chemistry, synthetic receptors, and single-cell spatial omics enable unprecedented insights into spatial, molecular, and functional aspects of cell-cell communication.
Quoted textsource-backed
highlights the latest advancements in molecular tools-such as super-resolution imaging, proximity labeling, bioorthogonal chemistry, synthetic receptors, and single-cell spatial omics-that enable unprecedented insights into spatial, molecular, and functional aspects of CCC
These molecular tool classes have translational implications for immuno-oncology, regenerative medicine, and autoimmune diseases.
Quoted textsource-backed
Emphasizing their translational potential, we discuss their profound implications for immuno-oncology, regenerative medicine, and autoimmune diseases.
Photoaffinity labeling and proximity labeling are described as techniques for elucidating lipid-protein interactions.
Quoted textsource-backed
To conclude, we survey techniques for elucidating lipid-protein interactions, including photoaffinity labeling and proximity labeling.