These ancient photosynthetic organisms possess a diverse array of restriction-modification (R-M) systems and CRISPR-Cas arrays that present challenges for genetic engineering, but also offer unique opportunities for cancer-targeted biotechnological applications.
First-pass extracted concept
restriction-modification systems
Aliases
R-M systems
Evidence Snippets
Supporting Sources
Linked Claims
Cyanobacterial defense systems may offer opportunities for cancer-targeted biotechnological applications.
but also offer unique opportunities for cancer-targeted biotechnological applications
Cyanobacterial restriction-modification systems may provide molecular machinery for precise recognition and targeting of cancer cells.
but also providing molecular machinery that could be harnessed for precise recognition and targeting of cancer cells
Cyanobacteria possess diverse restriction-modification systems and CRISPR-Cas arrays.
These ancient photosynthetic organisms possess a diverse array of restriction-modification (R-M) systems and CRISPR-Cas arrays
Widespread cyanobacterial restriction-modification systems create barriers to transformation.
creating formidable barriers to transformation
Cyanobacterial restriction-modification systems and CRISPR-Cas arrays present challenges for genetic engineering.
restriction-modification (R-M) systems and CRISPR-Cas arrays that present challenges for genetic engineering
A comprehensive genomic analysis of 126 cyanobacterial species found that 89% encode multiple restriction-modification systems with an average of 3.2 systems per genome.
A comprehensive genomic analysis of 126 cyanobacterial species found 89% encode multiple R-M systems, averaging 3.2 systems per genome
Prokaryotic defense systems are currently used in molecular applications as gene editing tools.
These systems exist in prokaryotes mainly as defense mechanisms but they are currently used in molecular applications as gene editing tools.