First-pass extracted concept

single-molecule localization microscopy

Candidate: concept label3 source documents4 linked claims
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Aliases

single-molecule based localization microscopy, SMLM

Evidence Snippets

The supplied source summary states that the review explicitly covers single-molecule localization microscopy (SMLM; including PALM, STORM/dSTORM, GSDIM).
Evidence 1Source 1DOIPubMedprovenance
Single-molecule localization microscopy (SMLM) image quality and resolution strongly depend on the photoswitching properties of fluorophores used for sample labeling.
Evidence 2Source 2DOIPubMedprovenance
single-molecule localization and image reconstruction ... This review will explain the principles and requirements of single-molecule based localization microscopy
Evidence 3Source 3DOIprovenance

Supporting Sources

Linked Claims

Claim 1dependency relationshipsupports2016Source 2DOIPubMed

SMLM image quality and resolution strongly depend on the photoswitching properties of fluorophores used for sample labeling.

Quoted textsource-backed
Single-molecule localization microscopy (SMLM) image quality and resolution strongly depend on the photoswitching properties of fluorophores used for sample labeling.
Claim 2method family membershipsupports2016Source 1DOIPubMed

The review groups PALM, STORM/dSTORM, and GSDIM under single-molecule localization microscopy.

Claim 3review scopesupports2016Source 1DOIPubMed

This review covers major super-resolution microscopy modality families including SIM, STED/RESOLFT, and single-molecule localization microscopy.

Claim 4performancesupports2011Source 3DOI

Single-molecule localization and image reconstruction based super-resolution fluorescence imaging can achieve optical resolution down to about 20 nm in the image plane.

Quoted textsource-backed
offers a comparatively simple way to achieve a substantially improved optical resolution down to ~20 nm in the image plane