First-pass extracted concept

sodium-glucose symporters

Candidate: concept label1 source documents4 linked claims

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Aliases

SGLTs

Evidence Snippets

At present, three classes of eukaryotic sugar transporters have been characterized, namely the glucose transporters (GLUTs), sodium-glucose symporters (SGLTs), and SWEETs.

Evidence 1Source 1DOI PubMedprovenance

Supporting Sources

Source 1review2015Annual Review of BiochemistryDOI PubMed

1 evidence snippet 4 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1application relevancesupports2015Source 1DOI PubMed

In plants, sugar transporters are important for crop yield and pathogen susceptibility.

Claim 2application relevancesupports2015Source 1DOI PubMed

Understanding sugar transport has therapeutic importance in humans, including relevance to diabetes and limiting sugar access of cancer cells.

Claim 3classification summarysupports2015Source 1DOI PubMed

The review states that three classes of eukaryotic sugar transporters had been characterized: GLUTs, SGLTs, and SWEETs.

Claim 4scope summarysupports2015Source 1DOI PubMed

Cellular exchange of sugars in multicellular organisms requires transport proteins that mediate uptake or release from cells or subcellular compartments.