In this special issue three important classes of stimuli-sensitive polymers are comprehensively described in reviews and progress reports: shape-memory polymers (SMPs), stimuli-responsive gels, and liquid crystalline elastomers (LCE).
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stimuli-responsive gels
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Enzymatically degradable hydrogels can be used as implantable scaffolds for induced autoregeneration and as miniscaffolds or injectable in-situ forming hydrogel systems for cell therapies.
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Enzymatically degradable hydrogels (Kloxin et al., DOI: 10.1002/adma.200904179) can be used as implantable scaffolds for induced autoregeneration as well as miniscaffolds or injectable in-situ forming hydrogel systems for cell therapies.
Hydrogels with on-demand volume changes can be used as coatings in cell culture devices to detach cell layers without enzymes by slightly increasing temperature.
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Hydrogels exhibiting volume changes on demand can be applied as coating in cell culture devices to detach cell layers without application of enzymes, e.g. by slightly increasing the temperature.
Stimuli-responsive hydrogels have high application potential in regenerative therapies as temporary substitutes of the extracellular matrix.
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Stimuli-responsive hydrogels have a high application potential in biomedical applications especially in regenerative therapies where they can act as a temporary substitute of the extracellular matrix.
The special issue highlights shape-memory polymers, stimuli-responsive gels, and liquid crystalline elastomers as three important classes of stimuli-sensitive polymers.
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In this special issue three important classes of stimuli-sensitive polymers are comprehensively described in reviews and progress reports: shape-memory polymers (SMPs), stimuli-responsive gels, and liquid crystalline elastomers (LCE).
In pH-responsive hydrogels, protonation and deprotonation of polymer network functional groups are faster processes than water diffusion in the network or phase separation leading to gel shrinkage.
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In pH-responsive hydrogels the protonation/deprotonation of functional groups of the polymer network chains is a fast process compared to the diffusion of water molecules in the polymer network structure or the phase separation leading to the shrinkage of the gel.