The term "resilience" refers to the ability to adapt successfully to stress, trauma and adversity... Stress resilience can be improved, but the outcomes and effects depend on the type of intervention and the species treated.
First-pass extracted concept
stress resilience
Candidate: concept label2 source documents7 linked claims
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Aliases
resilience phenotype, resilience to stress
Evidence Snippets
most stress-exposed individuals maintain normal psychological functioning (resilience to stress) ... the active mechanisms that underlie the resilience phenotype
Supporting Sources
Linked Claims
Resilience is the ability to adapt successfully to stress, trauma, and adversity, helping individuals avoid stress-induced mental disorders.
Stress resilience can be improved, but outcomes depend on the type of intervention and the species treated.
Evidence from animal models and humans is revealing neurophysiological and neuropsychological mechanisms underlying both stress susceptibility and resilience.
Understanding the neurobiological mechanisms of resilience should enable development of interventions that target neural circuitry and brain areas to enhance resilience and improve treatment of stress-induced disorders.
Accumulating evidence implicates genetic, epigenetic, and neurophysiological mechanisms in stress susceptibility and active mechanisms in resilience.
Quoted textsource-backed
An accumulating body of evidence is revealing the genetic, epigenetic, and neurophysiological mechanisms that underlie stress susceptibility, as well as the active mechanisms that underlie the resilience phenotype.
Only a minority of people exposed to prolonged stress develop stress-related psychiatric disorders including depression, while most maintain normal psychological functioning, indicating variation between susceptibility and resilience.
Quoted textsource-backed
a relatively small proportion of people (10-20%) experiencing prolonged stress develop stress-related psychiatric disorders, including depression (susceptibility to stress), whereas most stress-exposed individuals maintain normal psychological functioning (resilience to stress)
Pathological mechanisms of susceptibility are identified as potential therapeutic targets for depression treatment, and resilience-promoting mechanisms are reviewed as an alternative therapeutic strategy.
Quoted textsource-backed
key pathological mechanisms of susceptibility that are identified as potential therapeutic targets for depression treatment. We also review novel mechanisms that promote natural resilience as an alternative strategy to achieve treatment efficacy.