First-pass extracted concept

super-resolution microscopy

Candidate: concept label4 source documents6 linked claims
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Aliases

SRM

Extracted Explainers

What the tool is doing

Super-resolution microscopy is described as an advanced imaging approach that, when combined with lipid probes, enables detailed analysis of lipid organization.

Source 1DOIPubMed

Super-resolution microscopy is the imaging context in which the reviewed fluorogenic probes are applied. The abstract links improved signal-to-noise from fluorogenic probes to improved resolution.

Source 2DOIPubMed

Resources required

It requires super-resolution microscopy hardware and suitable lipid probes or sensors.

Source 1DOIPubMed

What problem it solves

It helps resolve lipid organization with high spatial detail and quantitative readout.

Source 1DOIPubMed

It is used for super-resolution imaging of cellular structures.

Source 2DOIPubMed

Alternatives

The abstract mentions ultrafast single-molecule imaging as another advanced microscopy approach used alongside these probes.

Source 1DOIPubMed

The abstract only mentions SRM broadly and does not compare specific super-resolution methods.

Source 2DOIPubMed

Evidence Snippets

Combined with state-of-the-art advanced microscopy approaches, including ultrafast single-molecule imaging and super-resolution microscopy, these probes facilitate high-resolution and quantitative analyses of lipid organization.
Evidence 1Source 1DOIPubMedprovenance
Herein we wish to fill this gap by providing the readers with an up-to-date summary of fluorogenic probes applied to super-resolution imaging of cellular structures.
Evidence 2Source 2DOIPubMedprovenance
different QD-based imaging applications will be discussed ... ranging from super-resolution microscopy and single-particle tracking over in vitro cell and tissue imaging to in vivo investigations.
Evidence 3Source 3DOIPubMedprovenance
These proteins offer the widest range of practical applications, including reversible high-density data bio-storage, photochromic FRET, and super-resolution microscopy by either point-scanning, structured illumination, or single molecule-based wide-field approaches.
Evidence 4Source 4DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1applicationsupports2025Source 1DOIPubMed

Lipid probes combined with ultrafast single-molecule imaging and super-resolution microscopy facilitate high-resolution and quantitative analyses of lipid organization.

Claim 2review gap statementsupports2018Source 2DOIPubMed

At the time of publication, there was no comprehensive review focused on fluorogenic probes suitable for super-resolution microscopy.

Quoted textsource-backed
Several excellent reviews summarize recent developments in SRM techniques, labeling techniques or different aspects of small synthetic fluorophores, however there is no comprehensive review on fluorogenic probes suitable for super-resolution microscopy.
Claim 3review scope statementsupports2018Source 2DOIPubMed

This review provides an up-to-date summary of fluorogenic probes applied to super-resolution imaging of cellular structures.

Quoted textsource-backed
Herein we wish to fill this gap by providing the readers with an up-to-date summary of fluorogenic probes applied to super-resolution imaging of cellular structures.
Claim 4review summarysupports2018Source 2DOIPubMed

Improved signal-to-noise from fluorogenic probes implies improved resolution in microscopy.

Quoted textsource-backed
Fluorogenic probes efficiently reduce non-specific background signals, which often results in highly improved signal-to-noise ratios. Although this implies improved resolution...
Claim 5application scopesupports2015Source 3DOIPubMed

QD-based imaging applications discussed in the review span super-resolution microscopy, single-particle tracking, in vitro cell and tissue imaging, and in vivo investigations.

Quoted textsource-backed
different QD-based imaging applications will be discussed from the technological and the biological point of view, ranging from super-resolution microscopy and single-particle tracking over in vitro cell and tissue imaging to in vivo investigations.
Claim 6application examplessupports2012Source 4DOIPubMed

Photoswitchable fluorescent proteins are used for reversible high-density data bio-storage, photochromic FRET, and super-resolution microscopy including point-scanning, structured illumination, and single molecule-based wide-field approaches.

Quoted textsource-backed
These proteins offer the widest range of practical applications, including reversible high-density data bio-storage, photochromic FRET, and super-resolution microscopy by either point-scanning, structured illumination, or single molecule-based wide-field approaches.