Synaptic plasticity is described as the cellular substrate for information storage in the central nervous system. In this review it is the main mechanistic bridge between circuit activity and memory.
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synaptic plasticity
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Long-term potentiation is treated as a foundational physiological model underlying synaptic plasticity accounts of memory in the review context.
The review context includes newer engram-focused framing that connects memory allocation and storage to synaptic modifications among identified engram cells.
The review context includes persistence and maintenance mechanisms such as synaptic tagging and PKMζ as relevant to how durable, input-specific synaptic changes could support memory storage.
The review evaluates whether long-term memory storage is explained primarily by synaptic plasticity or whether additional cell-intrinsic or non-synaptic mechanisms are required.
Learning-related synaptic plasticity within the corticohippocampal circuit during sensory experiences may enable adaptive behaviors for encoding spatial, episodic, social, and contextual memories.
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Finally, we offer insights about how learning-related synaptic plasticity within the corticohippocampal circuit during sensory experiences may enable adaptive behaviors for encoding spatial, episodic, social, and contextual memories.
Synaptic plasticity is presented as a cellular substrate for information storage in the central nervous system.
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Synaptic plasticity serves as a cellular substrate for information storage in the central nervous system.