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First-pass extracted concept

T-cell immune function

Candidate: concept label1 source documents4 linked claims
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Aliases

healthy T-cells, suppressed T-cells

Evidence Snippets

We have found that HS augments in vitro and in vivo immune function of healthy T-cells. In addition, HS restored the function of suppressed T-cells in vitro and in vivo.
Evidence 1Source 1PubMedprovenance

Supporting Sources

Linked Claims

Claim 1functional effectsupports1997Source 1PubMed

Hypertonic saline resuscitation augments immune function of healthy T-cells in vitro and in vivo.

Quoted textsource-backed
We have found that HS augments in vitro and in vivo immune function of healthy T-cells.
Claim 2mechanistic functionsupports1997Source 1PubMed

Hypertonic saline provides a costimulatory signal that enhances proliferation of activated T-cells.

Quoted textsource-backed
HS provides a costimulatory signal that enhances the proliferation of activated T-cells.
Claim 3rescue effectsupports1997Source 1PubMed

Hypertonic saline restores the function of suppressed T-cells in vitro and in vivo.

Quoted textsource-backed
HS restored the function of suppressed T-cells in vitro and in vivo
Claim 4therapeutic potentialsupports1997Source 1PubMed

Hypertonic saline may substitute for signals lost because of trauma-induced suppressive factors and thereby restore suppressed T-cell function.

Quoted textsource-backed
HS may be able to substitute signals lost through blockage as a result of trauma induced suppressive factors, thereby restoring the function of suppressed T-cells.