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transcranial ultrasound stimulation

Candidate: concept label1 source documents5 linked claims
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Aliases

TUS

Evidence Snippets

Transcranial ultrasound stimulation (TUS) is an emerging technology for non-invasive brain stimulation.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1consensus frameworksupports2025Source 1DOIPubMed

ITRUSST established consensus considerations for nonsignificant biophysical risk of transcranial ultrasound stimulation.

Quoted textsource-backed
The International Transcranial Ultrasonic Stimulation Safety and Standards consortium (ITRUSST) has established consensus on considerations for nonsignificant biophysical risk of TUS.
Claim 2evidence gapsupports2025Source 1DOIPubMed

Further data are needed to establish the threshold for significant risk in transcranial ultrasound stimulation.

Quoted textsource-backed
The stated levels are not safety limits per se, and further data is needed to establish the threshold for significant risk.
Claim 3safety thresholdsupports2025Source 1DOIPubMed

For mechanical effects in the stated use context, transcranial ultrasound stimulation is considered nonsignificant risk if MI or MI_tc does not exceed 1.9.

Quoted textsource-backed
For mechanical effects, it is non-significant risk if the mechanical index (MI) or the mechanical index for transcranial application (MI_tc) does not exceed 1.9.
Claim 4safety thresholdsupports2025Source 1DOIPubMed

For thermal effects in the stated use context, transcranial ultrasound stimulation is considered nonsignificant risk if peak temperature rise does not exceed 2 °C or peak absolute temperature does not exceed 39 °C assuming a 37 °C baseline.

Quoted textsource-backed
For thermal effects, it is non-significant risk if any of the following three levels are met: the peak temperature rise does not exceed 2 °C or the peak absolute temperature does not exceed 39 °C, assuming a baseline temperature of 37 °C
Claim 5safety thresholdsupports2025Source 1DOIPubMed

For thermal effects in the stated use context, transcranial ultrasound stimulation is considered nonsignificant risk if thermal dose does not exceed 2 CEM43 in brain tissue, 16 CEM43 in bone tissue, and 21 CEM43 in skin tissue.

Quoted textsource-backed
the thermal dose does not exceed 2 CEM43 in brain tissue, 16 CEM43 in bone tissue, and 21 CEM43 in skin tissue