First-pass extracted concept

ultrasound neuromodulation

Candidate: concept label4 source documents7 linked claims
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Extracted Explainers

What the tool is doing

Ultrasound is presented as a modality for regulating the nervous system. The abstract frames it as a mechanical vibration used for neural regulation.

Source 3DOIPubMed

What problem it solves

It offers a directionally controllable and spatially resolved way to influence neural activity.

Source 3DOIPubMed

What it does not solve

The abstract states that the mechanism of nervous-system regulation by ultrasound remains unclear.

Source 3DOIPubMed

Evidence Snippets

Ultrasound neuromodulation has emerged as a promising adjunctive therapy in Alzheimer's disease (AD).
Evidence 1Source 1DOIPubMedprovenance
The emerging NIBS treatment modality TPS demonstrates promising evidence in modulating symptoms in clinical population of neurocognitive disorders, common mental disorders, and neurodevelopmental disorders.
Evidence 2Source 2DOIPubMedprovenance
Due to its high spatial resolution, good directionality, and convenient operation in neural regulation, it has recently received increasing attention from scientists.
Evidence 3Source 3DOIPubMedprovenance
This article gives an overview on the state-of-the-art of the most recent application: ultrasound neuromodulation as a new brain therapy.
Evidence 4Source 4DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1therapeutic contextsupports2026Source 1DOIPubMed

Ultrasound neuromodulation has emerged as a promising adjunctive therapy in Alzheimer's disease.

Claim 2biophysical modelsupports2024Source 3DOIPubMed

The flexoelectric effect of the cell membrane and the soliton model suggest that action potential may also be a mechanical wave.

Quoted textsource-backed
Therefore, the flexoelectric effect of cell membrane and soliton model reveal that action potential may also be a mechanical wave.
Claim 3mechanism uncertaintysupports2024Source 3DOIPubMed

The mechanism by which ultrasound regulates the nervous system is still unclear.

Quoted textsource-backed
However, the mechanism by which ultrasound regulates the nervous system is still unclear.
Claim 4property advantagesupports2024Source 3DOIPubMed

Ultrasound has high spatial resolution, good directionality, and convenient operation for neural regulation.

Quoted textsource-backed
Due to its high spatial resolution, good directionality, and convenient operation in neural regulation, it has recently received increasing attention from scientists.
Claim 5therapeutic scopesupports2024Source 3DOIPubMed

Ultrasound has therapeutic effects on nervous system diseases including epilepsy, Parkinson's disease, and Alzheimer's disease.

Quoted textsource-backed
Finally, we also elaborated the therapeutic effect of ultrasound on nervous system disease such as epilepsy, Parkinson's disease, and Alzheimer's disease.
Claim 6clinical translationsupports2023Source 4DOIPubMed

The first treatment centers for ultrasound neuromodulation were not established until 2020 and clinical applications are spreading rapidly.

Quoted textsource-backed
Although research centers have existed for decades, the first treatment centers were not established until 2020, and clinical applications are spreading rapidly.
Claim 7state of fieldsupports2023Source 4DOIPubMed

Ultrasound neuromodulation is presented as a new brain therapy and the most recent of the listed ultrasound brain applications.

Quoted textsource-backed
This article gives an overview on the state-of-the-art of the most recent application: ultrasound neuromodulation as a new brain therapy.