We show in vivo that dorsal and ventral habenulae develop in different regions of prosomere 2.
First-pass extracted concept
ventral habenula
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Aliases
ventral habenulae, ventral habenular neurons
Evidence Snippets
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In zebrafish, dorsal and ventral habenulae develop in different regions of prosomere 2.
Quoted textsource-backed
We show in vivo that dorsal and ventral habenulae develop in different regions of prosomere 2.
Parapineal cell signals influence dorsal habenular neuron differentiation timing, such that dorsal habenular neurons differentiate while ventral habenular cells are still migrating toward their final destination.
Quoted textsource-backed
Influenced by signals from parapineal cells, dorsal habenular neurons differentiate at a time at which ventral habenular cells are still on their way towards their final destination.
Functional tcf7l2 gene activity is required for ventral habenula formation in zebrafish.
Quoted textsource-backed
In the process of ventral habenula formation, functional tcf7l2 gene activity is required and in its absence, ventral habenular neurons do not develop.
Differential developmental timing between dorsal and ventral habenular populations may explain why only dorsal habenular neuronal populations differ in size across brain hemispheres.
Quoted textsource-backed
Thus, our finding may provide a simple explanation as to why only neuronal populations of the dorsal habenulae differ in size across brain hemispheres.
In the absence of functional tcf7l2 activity, ventral habenular neurons do not develop.
Quoted textsource-backed
In the process of ventral habenula formation, functional tcf7l2 gene activity is required and in its absence, ventral habenular neurons do not develop.