First-pass extracted concept

ventricular-subventricular zone (V-SVZ) neurogenesis

Candidate: concept label1 source documents5 linked claims
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Aliases

adult V-SVZ neurogenesis, V-SVZ neurogenesis

Evidence Snippets

Here, we review a broad range of discoveries that have emerged from studies of postnatal V-SVZ neurogenesis
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1cell identity summarysupports2016Source 1DOIPubMed

Adult V-SVZ neural stem cells were identified as a subpopulation of astroglial cells.

Claim 2lineage relationshipsupports2016Source 1DOIPubMed

V-SVZ neural stem cells produce neuroblasts that migrate to the olfactory bulb and differentiate into local circuit interneurons.

Claim 3mechanism summarysupports2016Source 1DOIPubMed

Cell-intrinsic molecular mechanisms enable lifelong neurogenesis in the V-SVZ.

Claim 4review scope summarysupports2016Source 1DOIPubMed

Adult V-SVZ neural stem/precursor cells persist in the walls of the lateral ventricles.

Claim 5translational relevancesupports2016Source 1DOIPubMed

Expanding knowledge of V-SVZ neural stem cell biology may inform regenerative therapies from cultured and endogenous human neural precursors.