very early recurrence

Identifying patients with grade 3 tumors, pancreatic head tumors, or elevated red cell distribution width may support tailored intensive surveillance and consideration of early adjuvant therapy.

Very early recurrence in pancreatic ductal adenocarcinoma is defined here as recurrence within 12 weeks after curative-intent surgery.

Approximately 50% of patients experience recurrence within one year after curative-intent surgery for pancreatic ductal adenocarcinoma.

Random forest modelling increased predictive accuracy for very early recurrence by identifying nonlinear patterns in the data.

Very early recurrence is associated with higher six-month mortality than later recurrence in the discussed pancreatic cancer setting.

Abnormal red cell distribution width is identified as a risk factor for very early recurrence.

Pancreatic head tumor location is associated with very early recurrence.

Poorly differentiated grade 3 tumor is highlighted as the strongest predictor of very early recurrence.