First-pass extracted concept

alternative pre-mRNA splicing

Candidate: toolkit item1 source documents6 linked claims
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Aliases

alternative splicing, AS

Evidence Snippets

Alternative splicing (AS) is a major post-transcriptional mechanism to enhance the diversity of proteome in response to environmental signals.
Evidence 1Source 1DOIPubMedprovenance

Supporting Sources

Linked Claims

Claim 1future directionsupports2016Source 1DOIPubMed

Combining genetic study with high-throughput analyses of alternative splicing and splicing complexes in response to light is proposed as a way to advance mechanistic understanding of light control of alternative splicing and plant development.

Quoted textsource-backed
The combination of genetic study and high-throughput analyses of AS and splicing complexes in response to light is likely to further advance our understanding of the molecular mechanisms underlying light control of AS and plant development.
Claim 2mechanistic hypothesissupports2016Source 1DOIPubMed

Alternative splicing of mRNAs encoding photoreceptors may participate in feedback control of alternative splicing.

Quoted textsource-backed
we also discuss the possibility that AS of the mRNAs encoding photoreceptors may be involved in feedback control of AS
Claim 3mechanistic hypothesissupports2016Source 1DOIPubMed

Sensory photoreceptors and retrograde signaling pathways may coordinately regulate alternative splicing of pre-mRNAs in plants.

Quoted textsource-backed
we summarize current progresses on how light affects AS, and how sensory photoreceptors and retrograde signaling pathways may coordinately regulate AS of pre-mRNAs
Claim 4mechanistic hypothesissupports2016Source 1DOIPubMed

The review hypothesizes that light-mediated regulation of splicing-factor expression and activity is a major mechanism underlying light-regulated alternative splicing.

Quoted textsource-backed
We hypothesize that light regulation of the expression and activity of splicing factors would be a major mechanism of light-mediated AS.
Claim 5review summarysupports2016Source 1DOIPubMed

Alternative splicing is described as a major post-transcriptional mechanism that increases proteome diversity in response to environmental signals.

Quoted textsource-backed
Alternative splicing (AS) is a major post-transcriptional mechanism to enhance the diversity of proteome in response to environmental signals.
Claim 6review summarysupports2016Source 1DOIPubMed

The review states that little is known about the mechanisms by which light affects alternative splicing at the post-transcriptional level in plants.

Quoted textsource-backed
Although light-mediated gene expression has been widely investigated, little is known regarding the mechanism of light affecting AS to modulate mRNA at the post-transcriptional level.