few detailed analyses have been carried out on the control of transcription start sites (TSSs)
First-pass extracted concept
alternative transcription start sites
Candidate: toolkit item1 source documents6 linked claims
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Aliases
transcription start sites, TSSs
Evidence Snippets
Supporting Sources
Linked Claims
Thousands of genes in Arabidopsis seedlings use multiple transcription start sites.
Quoted textsource-backed
Thousands of genes use multiple TSSs
Translation efficiencies of genes with enhanced usage of downstream TSSs increase upon blue light exposure.
Quoted textsource-backed
Translation efficiencies of the genes showing enhanced usage of these TSSs increased upon BL exposure.
Blue-light-regulated downstream TSS usage occurs in HY5 and HYH.
Quoted textsource-backed
This type of regulation is found in <i>HY5</i> and <i>HYH</i>, major regulators of light-dependent gene expression.
Transcripts from TSSs upstream of uORFs accumulated in an NMD mutant for 45 of the 220 genes, including HY5.
Quoted textsource-backed
We also show that transcripts from TSSs upstream of uORFs in 45 of the 220 genes, including <i>HY5</i>, accumulated in a mutant of NMD.
Blue light enhances transcription from transcription start sites located downstream of uORFs in 220 genes.
Quoted textsource-backed
Transcription from TSSs located downstream of the uORFs in 220 genes is enhanced by BL exposure.
Blue light controls gene expression not only by enhancing transcription but also by choosing transcription start sites, and transcripts from downstream TSSs evade uORF-mediated inhibition to ensure high expression of light-regulated genes.
Quoted textsource-backed
These results suggest that BL controls gene expression not only by enhancing transcriptions but also by choosing the TSS, and transcripts from downstream TSSs evade uORF-mediated inhibition to ensure high expression of light-regulated genes.