First-pass extracted concept

Arabidopsis cryptochrome 1

Candidate: toolkit item2 source documents8 linked claims

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Aliases

cry1, CRY1

Evidence Snippets

Arabidopsis cryptochrome 1 (CRY1)

Evidence 1Source 1DOI PubMedprovenance

we estimate the in vivo half-lives of the signaling states of cry1 and cry2

Evidence 2Source 2DOI PubMedprovenance

Supporting Sources

Source 1primary paper2017The Plant JournalDOI PubMed

1 evidence snippet 5 linked claims Claim 1 Claim 2 Claim 3

Source 2primary paper2013The Plant JournalDOI PubMed

1 evidence snippet 3 linked claims Claim 1 Claim 2 Claim 3

Linked Claims

Claim 1feedback circuitsupports2017Source 1DOI PubMed

CRY and BIC form a negative-feedback circuitry that regulates each other's activity.

Quoted textsource-backed

These results demonstrate a CRY-BIC negative-feedback circuitry that regulates the activity of each other.

Claim 2pathway mechanismsupports2017Source 1DOI PubMed

Cryptochromes activate BIC gene transcription by suppressing COP1 activity, resulting in activation of HY5 associated with chromatins of the BIC promoters.

Quoted textsource-backed

by suppressing the activity of CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1), resulting in activation of the transcription activator ELONGATED HYPOCOTYL 5 (HY5) that is associated with chromatins of the BIC promoters

Claim 3physiological functionsupports2017Source 1DOI PubMed

Photoreceptor co-action in activating BIC transcription may sustain blue light sensitivity of plants under broad spectra of solar radiation in nature.

Quoted textsource-backed

suggesting a novel photoreceptor co-action mechanism to sustain blue light sensitivity of plants under the broad spectra of solar radiation in nature.

Claim 4regulatory mechanismsupports2017Source 1DOI PubMed

BIC1 and BIC2 inhibit Arabidopsis cryptochrome function by blocking blue light-dependent cryptochrome dimerization.

Quoted textsource-backed

two negative regulators of Arabidopsis cryptochromes, Blue light Inhibitors of Cryptochromes 1 and 2 (BIC1 and BIC2), inhibit cryptochrome function by blocking blue light-dependent cryptochrome dimerization

Claim 5transcriptional regulationsupports2017Source 1DOI PubMed

Cryptochromes mediate light activation of transcription of the BIC genes.

Quoted textsource-backed

Here we show that cryptochromes mediate light activation of transcription of the BIC genes

Claim 6comparative stabilitysupports2013Source 2DOI PubMed

Plant cryptochrome signaling state lifetimes are not, or are only moderately, stabilized in planta relative to other measured contexts.

Quoted textsource-backed

Thus, the signaling state lifetimes of plant cryptochromes are not, or are only moderately, stabilized in planta.

Claim 7lifetime measurementsupports2013Source 2DOI PubMed

The in vivo half-life of the signaling state of Arabidopsis cry1 is about 5 minutes.

Quoted textsource-backed

we estimate the in vivo half-lives of the signaling states of cry1 and cry2 to be in the range of 5 and 16 min, respectively

Claim 8lifetime measurementsupports2013Source 2DOI PubMed

The lifetime of the Arabidopsis cry1 lit state in insect cells is approximately 6 minutes.

Quoted textsource-backed

the lifetime of the Arabidopsis cry1 lit state in insect cells was found to be ~6 min