Because calcium integrin-binding protein1 lacks a suitable pocket that could be used to create a chemical inhibitor... Currently, no FDA-approved drugs are available for CIB1-driven cancer.
First-pass extracted concept
calcium integrin-binding protein1
Candidate: toolkit item1 source documents3 linked claims
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Aliases
calcium integrinbinding protein1, CIB1
Evidence Snippets
Supporting Sources
Linked Claims
Improved understanding of CIB1 structure and function has enabled the design of several therapeutic candidates.
Quoted textsource-backed
The structure and function of the newly discovered calcium integrinbinding protein1 have been improved, paving the way for the designing of several therapeutic candidates.
CIB1 is a challenging drug target because it lacks a suitable pocket for creating a chemical inhibitor and is highly resistant to small inhibitors.
Quoted textsource-backed
Because calcium integrin-binding protein1 lacks a suitable pocket that could be used to create a chemical inhibitor... CIB1 has proven to challenge drug target due to several factors, including the fact that the CIB1 protein is highly resistant to small inhibitors.
No FDA-approved drugs are available for CIB1-driven cancer.
Quoted textsource-backed
Currently, no FDA-approved drugs are available for CIB1-driven cancer.