Cas9 is presented as a CRISPR-associated enzyme used for gene editing. In the abstract, it sits within a system that enables insertion or deletion of genes to modify genomes and influence phenotype.
First-pass extracted concept
Cas9
Candidate: toolkit itemType: protein domain2 source documents6 linked claims
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Aliases
Cas9 enzyme, CRISPR-associated protein 9
Extracted Explainers
What the tool is doing
Resources required
What problem it solves
Evidence Snippets
The Cas9 enzyme is the most widely used within the CRISPR framework and has already received approval for treating sickle cell disease, with many other applications likely to follow.
The Cas9 protein (CRISPR-associated protein 9) ... is emerging as a powerful tool for engineering the genome in diverse organisms.
Supporting Sources
Linked Claims
Cas9 has already received approval for treating sickle cell disease.
Cas9 is the most widely used enzyme within the CRISPR framework.
Possible applications of Cas9 in biomedical research and therapeutics are only beginning to be explored.
Quoted textsource-backed
With all of these advances, we have just begun to explore the possible applications of Cas9 in biomedical research and therapeutics.
Cas9 is described as a powerful tool for engineering the genome in diverse organisms.
Quoted textsource-backed
The Cas9 protein ... is emerging as a powerful tool for engineering the genome in diverse organisms.
Development of Cas9 as a tool made sequence-specific gene editing several magnitudes easier.
Quoted textsource-backed
its development as a tool has made sequence-specific gene editing several magnitudes easier
Cas9 is an RNA-guided DNA endonuclease that can be reprogrammed to new target sites by changing the guide RNA sequence.
Quoted textsource-backed
As an RNA-guided DNA endonuclease, Cas9 can be easily programmed to target new sites by altering its guide RNA sequence